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Book Chapter

Deep Learning Architectures for Biomedical Signal Intelligence and Early Disease Prediction

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Moosa Swarnalatha
Assistant Professor, Department of Artificial Intelligence, Anurag University, Venkatapur, Ghatkesar, Medchal, Telangana, India.
Pages: 12-23
Keywords: Deep Learning; Biomedical Signal Processing; Early Disease Prediction; CNN-LSTM-SE; Arrhythmia Classification; Electrocardiogram (ECG).

Abstract

The integration of deep learning (DL) into biomedical signal processing has catalyzed a paradigm shift in healthcare, enabling the development of intelligent systems for early disease prediction and diagnosis. This chapter provides a comprehensive exploration of advanced DL architectures tailored for biomedical signal intelligence. We introduce a novel hybrid model, the CNN-LSTM-SE, which synergistically combines Convolutional Neural Networks (CNNs) for spatial feature extraction, Long Short-Term Memory (LSTM) networks for capturing temporal dependencies, and a Squeeze-andExcitation (SE) module for adaptive channel-wise feature recalibration. Using the MITBIH Arrhythmia Database as a case study, we demonstrate the model’s exceptional performance in classifying cardiac arrhythmias, achieving an accuracy of 98.5%. The chapter details the complete workflow, from signal preprocessing and data augmentation to model architecture, training, and evaluation. A significant portion is dedicated to the in-depth analysis of the results, including performance metrics, confusion matrices, and comparative assessments against other DL models. We conclude by discussing the implications of these findings for the future of predictive medicine and outlining potential avenues for further research. This work serves as a practical guide for researchers and practitioners seeking to leverage the power of deep learning for building robust and accurate biomedical prediction systems.

References

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  2. Ao Sun et al. “An arrhythmia classification model based on a CNN-LSTM-SE al￾gorithm”. In: Sensors 24.19 (2024), p. 6306.
  3. Ashish Khanna et al. “Internet of things and deep learning enabled healthcare dis￾ease diagnosis using biomedical electrocardiogram signals”. In: Expert Systems 40.4 (2023), e12864.
  4. Walid A Zgallai. Biomedical signal processing and artificial intelligence in healthcare. Academic Press, 2020.
  5. Chensi Cao et al. “Deep learning and its applications in biomedicine”. In: Genomics, proteomics & bioinformatics 16.1 (2018), pp. 17–32.
  6. Prabu Pachiyannan et al. “A novel machine learning-based prediction method for early detection and diagnosis of congenital heart disease using ECG signal processing”. In: Technologies 12.1 (2024), p. 4.
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